18F-labelled folate/antifolate analogues
US10357576B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | May 8, 2013 |
| Grant date | Jul 23, 2019 |
| Priority date | — |
| Expiry date | Mar 27, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/705
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed towards new 18F-folate/antifolate analog radiopharmaceuticals, wherein the phenyl group within folate structures has been replaced by an 18F-heterocycle, their precursors, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.