Substituted 2-N-hydroxy-1,3-dioxo-1,2,3,4-tetrahydronaphthyridines, and methods of making and using same
US10358447B2 · kind B2 · utility
2Cited by
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24Claims
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Assignee
Inventors
Key dates
| Filing date | Nov 29, 2018 |
| Grant date | Jul 23, 2019 |
| Priority date | — |
| Expiry date | Nov 29, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention includes novel substituted 2-N-hydroxy-1,3-dioxo-1,2,3,4-tetrahydronaphthyridines, which can be used to treat or prevent hepatitis B virus (HBV) infections in a patient. In certain embodiments, the compounds and compositions of the invention inhibit HBV RNAse H activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.