Patent · US Active

Treatment of atopic dermatitis and asthma using RNA complexes that target IL4Rα, TRPA1, or F2RL1

US10358648B2 · kind B2 · utility

8Cited by
2References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 1, 2017
Grant dateJul 23, 2019
Priority date
Expiry dateFeb 1, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/3521
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In certain aspects, provided herein are RNA complexes (e.g., asymmetric RNA complexes, such as asiRNAs or cell penetrating asiRNAs) that inhibit IL4Rα, TRPA1, and/or F2RL1 expression and are therefore useful for treating atopic dermatitis or asthma.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.