Patent · US Active

Method of production of 2,4-dihydroxybutyric acid

US10358663B2 · kind B2 · utility

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41Claims
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Key dates

Filing dateNov 18, 2015
Grant dateJul 23, 2019
Priority date
Expiry dateNov 18, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y102/01011
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway that includes transforming malate into 4-phospho-malate using a malate kinase, then transforming 4-phospho-malate into malate-4-semialdehyde using a malate semialdehyde dehydrogenase, and then transforming malate-4-semialdehyde into 2,4-DHB using a DHB dehydrogenase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.