Near infrared photonic prostatoscopy analyzer

US10362983B2 · kind B2 · utility

Inventors

• Robert R. Alfano · New York, US
• Wubao Wang · Great Neck, US
• Yang Pu · Beihai, CN
• Yury Budansky · Oakland, US
• Laura A. Sordillo · New York, US
• Guichen Tang · Great Neck, US
• James Eastham · Tarrytown, US

Key dates

• Filing date: May 12, 2015
• Grant date: Jul 30, 2019
• Expiry date: Oct 20, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B5/0086
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A rectal near infrared (NIR) scanning polarization imaging system uses NIR Photonic Prostatoscopy Analyzer (NIRPPA) for prostate cancer detection using light. The NIRPPA consists of a portable rectal NIR scanning polarization imaging unit and an optical fiber-based rectal probe capable of recording sets of 2D images of a prostate through rectum at different wavelengths and depths and obtaining a three dimensional (3D) image of the prostate and 3D locations of abnormal tissue inside the prostate. Diode lasers/light emission diodes (LEDs) with selected emitting wavelengths are used in the NIR spectral range from 650 nm to 2,400 nm corresponding to the four tissue optical windows (#I, 650 nm-950 nm; #II, 1,100 nm-1,350 nm; #III, 1,600 nm-1,870 nm; and #IV, 2,100 nm-2,300 nm). The fingerprint absorptions of water (H2O), Oxyhemoglobin (HbO2) and deoxyhemoglobin (Hb) in the prostate are used as native biomarkers for prostate cancer detection.