Patent · US Active

(+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof

US10363251B2 · kind B2 · utility

0Cited by

9References

12Claims

0Family size

Assignee

MALLINCKRODT LLC · US

Inventors

Bobby N. Trawick · Florissant, US
David W. Berberich · Saint Peters, US
Christopher W. Grote · Webster Groves, US

Key dates

Filing date	Jul 31, 2015
Grant date	Jul 30, 2019
Priority date	—
Expiry date	Jul 31, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D489/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides (+)-morphinans comprising Toll-like receptor 9 (TLR9) antagonist activity, as well as methods for using the (+)-morphinans to treat a variety of disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.