Methods for treatment of retinal disease by photoreceptor gene expression modulation

US10363256B2 · kind B2 · utility

Assignees

• University of Washington · US
• The J. David Gladstone Institute, a testamentary trust established under the Will of J. David Gladstone · US

Inventors

• Thomas A. Reh · Seattle, US
• Paul Nakamura · Seattle, US
• Sheng Ding · San Diego, US

Key dates

• Filing date: Mar 28, 2016
• Grant date: Jul 30, 2019
• Expiry date: Mar 28, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods for decreasing rod gene expression in a retina, methods for decreasing the protein products expressed by rod genes in a retina, methods for treating a disease or condition treatable by decreasing rod gene expression or their protein products in a retina, and methods for treating a retinal disease in a subject.