Hydrophobic modified peptides for liver specific diagnosis

US10363323B2 · kind B2 · utility

Assignee

• RUPRECHT - KARLS - UNIVERSITÄT HEIDELBERG · DE

Inventors

• Walter Mier · Bensheim, DE
• Stephan Urban · Neustadt, DE
• Stefan Mehrle · Schifferstadt, DE
• Uwe Haberkorn · Schwetzingen, DE
• Thomas Müller · Biberach, DE
• Vasileios ASKOXYLAKIS · Wilhelmsfeld, DE

Key dates

• Filing date: Feb 10, 2012
• Grant date: Jul 30, 2019
• Expiry date: Feb 10, 2032

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to hydrophobic modified peptides for the specific delivery of labels to the liver, preferably to hepatocytes, in vitro as well as in vivo. The present invention relates to pharmaceutical compositions comprising said hydrophobic modified peptide(s) and the label(s) to be specifically delivered to the liver. The present invention furthermore relates to the diagnostic use of the inventive hydrophobic modified peptides as well as to a method for the diagnosis of liver diseases or disorders.