Patent · US Active

Cyclic phosphates and cyclic phosphoramidates for the treatment of neurologic disorders

US10364263B2 · kind B2 · utility

0Cited by

0References

22Claims

0Family size

Assignee

RETROPHIN, INC. · US

Inventors

Maria Beconi · Bedford, US
Daniel Elbaum · Newton, US
Steven Harper · Roma, IT
Savina Malancona · Pomezia, IT

Key dates

Filing date	Dec 8, 2016
Grant date	Jul 30, 2019
Priority date	—
Expiry date	Dec 8, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F9/6552
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds having the following formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, D, E and R1 are as defined herein, are provided. Methods comprising the use of such compounds for the treatment of neurological disorders, such as pantothenate kinase-associated neurodegeneration, and pharmaceutical compositions containing such compounds, and their use in the treatment of neurological disorders, also are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.