Patent · US Active

Bioluminescent assays utilising secreted luciferases

US10364454B2 · kind B2 · utility

0Cited by
5References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 30, 2016
Grant dateJul 30, 2019
Priority date
Expiry dateApr 16, 2037

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/182
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Disclosed herein are methods for determining the amount or activity of one or more luciferases and methods for measuring the luminescent signal generated by one or more luciferases in a sample, the methods comprising incubating the sample with a reactive substrate(s) of the luciferase(s) to be analyzed and a reducing agent to inactivate a first luciferase, wherein the first luciferase, in its native form, is a secreted luciferase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.