Two-mode Raman optical projection tomography system
US10365219B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 28, 2019 |
| Grant date | Jul 30, 2019 |
| Priority date | — |
| Expiry date | Jan 28, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/1787
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention discloses a two-mode Raman optical projection tomography system. Samples are irradiated by the laser beam after the beam being expanded by beam expander. Optical signal of each mode will be separated by the beam splitter. Sparse sampling method is used for signal collection. Optical transmission projection signal acquisition module collects transmitted light of samples to form optical projection image. Multi-spectral Raman scattering signal acquisition module collects Raman scattering light produced by samples. Background noise is removed from the collected data. Sparse sampling data are reconstructed by using algebraic reconstruction method (ART) based on TV minimization. The three-dimensional structure image obtained by reconstruction and the three-dimensional chemical compositions image are fused to obtain the three-dimensional volume image with multiple information.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.