Patent · US Active

Non-protein clostridial toxin compositions

US10369190B2 · kind B2 · utility

9Cited by

1References

2Claims

0Family size

Assignee

Allergan, Inc. · US

Inventors

Maurice Abiad · Anaheim, US
Bhas Dani · San Diego, US
Evgenyi Shalaev · Old Lyme, US

Key dates

Filing date	Sep 13, 2017
Grant date	Aug 6, 2019
Priority date	—
Expiry date	Sep 13, 2037

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Pharmaceutical compositions that stabilize a Clostridial toxin active ingredient are described. The compositions can be liquid or solid compositions, and comprise a surfactant and an antioxidant. In some embodiments, the compositions comprise a surfactant selected from a poloxamer and a polysorbate; an antioxidant selected from methionine, N-acetyl cysteine, ethylenediaminetetraacetic acid and combinations thereof, and, optionally, a tonicity agent and/or a lyoprotector selected from, for example, trehalose, sucrose.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.