Divalent nucleobase compounds and uses therefor
US10370415B2 · kind B2 · utility
4Cited by
6References
47Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 11, 2014 |
| Grant date | Aug 6, 2019 |
| Priority date | — |
| Expiry date | Jan 5, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5308
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described herein are novel divalent nucleobases that each bind two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone (a genetic recognition reagent, or genetic recognition reagent). In one embodiment, the genetic recognition reagent is a peptide nucleic acid (PNA) or gamma PNA (?PNA) oligomer. Uses of the divalent nucleobases and monomers and genetic recognition reagents containing the divalent nucleobases also are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.