Claudin-6-specific immunoreceptors and T cell epitopes

US10370423B2 · kind B2 · utility

Assignees

• Biotech Cell & Gene thrapies GMBH · DE
• TRON—Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz · DE
• Ganymed Pharmaceuticals GmbH · DE

Inventors

• Ugur Sahin · Mainz, DE
• Ozlem Tureci · Homburg, DE
• Petra Simon · Mainz, DE
• Tana Omokoko · Mainz, DE
• Holger Hoff · Mainz, DE
• Ralf-Holger Voss · Ingelheim am Rhein, DE
• Andrea BREITKREUZ · Worms, DE
• Kathleen HOBOHM · Kelkheim, DE
• Karolina Anna Mroz · Wiesbaden, DE

Key dates

• Filing date: Mar 30, 2015
• Grant date: Aug 6, 2019
• Expiry date: Sep 15, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides Claudin-6-specific immunoreceptors (T cell receptors and artificial T cell receptors (chimeric antigen receptors; CARs)) and T cell epitopes which are useful for immunotherapy.