System and method for laser imaging and ablation of cancer cells using fluorescence
US10376148B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 5, 2013 |
| Grant date | Aug 13, 2019 |
| Priority date | — |
| Expiry date | Oct 3, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2018/00577
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.