Crystal of aniline pyrimidine compound of trifluoroethyl substituted indole and salt thereof
US10376512B1 · kind B1 · utility
2Cited by
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14Claims
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Key dates
| Filing date | Aug 9, 2018 |
| Grant date | Aug 13, 2019 |
| Priority date | — |
| Expiry date | Aug 9, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure relates to a crystal of an aniline pyrimidine compound of trifluoroethyl substituted indole and a salt thereof as an EGFR inhibitor, specifically relates to a crystal of a compound represented by formula I, a crystal of monomethyl sulfonate of the compound represented by formula I or a crystal of dimethyl sulfonate of the compound represented by formula I, and further relates to a method for preparing the crystal, a crystalline composition comprising the crystal, or a pharmaceutical composition comprising the crystal or a crystalline composition thereof, and a medical use thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.