Immunogenic composition for preventing pneumococcal diseases and preparation method thereof
US10376572B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 28, 2017 |
| Grant date | Aug 13, 2019 |
| Priority date | — |
| Expiry date | Apr 28, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55588
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides an immunogenic composition for preventing pneumococcal diseases, comprising PspA-MRX1, PspA-EF5668, PspA-EF3296 and PlyL460D, wherein the amount of each component is 10-100 μg/ml; the immunogenic composition is prepared by adding to aluminum adjuvant the corresponding dosages of the four stock solutions PspA-mRX1, PspA-EF5668, PspA-EF3296 and PlyL460D, and mixing them homogeneously; the immunogenic composition can prevent infection and invasion by Streptococcus pneumonia, covering more than 95% of the strains in clinic. The immunogenic composition has a wide application in the prevention of pneumonia, and is suitable for large-scale production in industry for its simple preparation method, low production cost, and short production cycle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.