Antigen binding proteins that bind c-met

US10377827B2 · kind B2 · utility

Assignee

• SORRENTO THERAPEUTICS, INC. · US

Inventors

• Barbara A. Swanson · Encinitas, US
• Heyue Zhou · San Diego, US
• Yan Zhang · New Albany, US
• Randy Gastwirt · San Diego, US
• John Dixon Gray · Union, US

Key dates

• Filing date: Jun 21, 2013
• Grant date: Aug 13, 2019
• Expiry date: Oct 2, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There is disclosed compositions and methods relating to or derived from anti-c-Met antibodies. More specifically, there is disclosed fully human antibodies that bind c-Met, c-Met-binding fragments and derivatives of such antibodies, and c-Met-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having c-Met related disorders or conditions, including various inflammatory disorders and various cancers.