Vector and gene introduction agent for monitoring and visualizing cell differentiation using expression of micro RNA as indicator and monitoring and visualizing method using thereof
US10378070B2 · kind B2 · utility
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Key dates
| Filing date | Sep 7, 2017 |
| Grant date | Aug 13, 2019 |
| Priority date | — |
| Expiry date | Sep 7, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/912
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided is a method for continuously visualizing and accurately determining a living cellular state per se. Disclosed are: a vector comprising 5′- and 3′-end nucleic acid sequences for integration and a reporter gene sequence positioned between the 5′- and 3′-end nucleic acid sequences for integration; a gene introduction agent comprising a first vector and a second vector; a cell comprising the vector or the agent; and a method for determining a cellular state by using the cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.