Tumor suppressor VSTM2A as a biomarker for colorectal cancer
US10379124B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Apr 5, 2017 |
| Grant date | Aug 13, 2019 |
| Priority date | — |
| Expiry date | Apr 5, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/56
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method for diagnosing and determining prognosis of colorectal cancer in a subject by detecting suppressed expression of the VSTM2A gene, which in some cases is due to elevated methylation level in the genomic sequence of this gene. A kit and device useful for such a method are also provided. In addition, the present invention provides a method for treating colorectal cancer by increasing VSTM2A gene expression or activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.