Patent · US Active

Non-invasive method and system for characterizing cardiovascular systems for all-cause mortality and sudden cardiac death risk

US10383535B2 · kind B2 · utility

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Key dates

Filing dateMar 30, 2018
Grant dateAug 20, 2019
Priority date
Expiry dateMar 30, 2038

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG16Z99/00
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Methods and systems for evaluating the electrical activity of the heart to identify novel ECG patterns closely linked to the subsequent development of serious heart rhythm disturbances and fatal cardiac events. Two approaches are describe, for example a model-based analysis and space-time analysis, which are used to study the dynamical and geometrical properties of the ECG data. In the first a model is derived using a modified Matching Pursuit (MMP) algorithm. Various metrics and subspaces are extracted to characterize the risk for serious heart rhythm disturbances, sudden cardiac death, other modes of death, and all-cause mortality linked to different electrical abnormalities of the heart. In the second method, space-time domain is divided into a number of regions (e.g., 12 regions), the density of the ECG signal is computed in each region and input to a learning algorithm to associate them with these events.

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