Microarray with polymer-free microstructures, methods of making, and methods of use
US10384045B2 · kind B2 · utility
5Cited by
264References
18Claims
0Family size
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Key dates
| Filing date | Mar 10, 2014 |
| Grant date | Aug 20, 2019 |
| Priority date | — |
| Expiry date | Aug 7, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A microprojection array comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a therapeutic macromolecule and a stabilizing excipient. Described herein are microstructures having a proximal and distal layer, wherein the distal layer which contains the therapeutic molecule does not rely on the presence of a structure-forming polymer to impart the mechanical strength necessary to penetrate the skin. Methods of forming the array, and methods of using the array are contemplated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.