Assay apparatus and methods
US10384207B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 19, 2016 |
| Grant date | Aug 20, 2019 |
| Priority date | — |
| Expiry date | Dec 1, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5008
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Apparatus and methods for determining whether a test compound induces cell activity, changes cell activity, prevents cell activity, or inhibits cell activity. An embodiment comprises placing a test compound solution in contact with a cell suspension media containing cells, diffusing the test compound solution into the cell suspension from one or more sides, and detecting activity in the cells with respect to their distance from the side from which the test compound is diffusing. Embodiments may provide an apparatus that allows a side source, a point source, or both, from which a test compound solution diffuses into a cell suspension media and contacts cells. Detecting cell activity may involve detecting activity in a first cell group proximate to the side from which the test compound is diffusing, and detecting activity in a second cell group farther than the first cell group from the side from which the test compound is diffusing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.