Terpene derivative-based PAR1 inhibitor, preparation method thereof, and use in treatment of thrombotic diseases
US10385041B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Jan 14, 2016 |
| Grant date | Aug 20, 2019 |
| Priority date | — |
| Expiry date | Jan 14, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel terpene derivative-based PAR1 inhibitor, a preparation method thereof and a pharmaceutical composition including the same or a salt thereof, as well as a use of the PAR1 inhibitor and the salt thereof in preparation of medicaments for preventing and/or treating thrombotic diseases. The structural formula of the compound is as follows:The compound has the advantages of clear target, novel structure, low bleeding risk, high safety, outstanding active effect, low preparation cost and the like, and has a great application prospect in the preparation of the medicaments for treating the thrombotic diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.