4-substituted pyrrolo[2,3-d]pyrimidine compound and use thereof
US10385056B2 · kind B2 · utility
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Key dates
| Filing date | Mar 24, 2015 |
| Grant date | Aug 20, 2019 |
| Priority date | — |
| Expiry date | Mar 24, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a 4-substituted pyrrolo[2,3-d]pyrimidine compound and the use thereof in preparing medications for treating JAK-targeted diseases such as rheumatoid, immune system diseases, and tumor. The 4-substituted pyrrolo[2,3-d]pyrimidine compound of the invention is as shown in chemical formula I.The activity experimental results of the invention show that the new compound has obvious effect and activity in inhibition of Janus kinases, JAK-STAT, cell proliferation of human lymphocytoma, and rheumatoid arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.