Recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism
US10385320B2 · kind B2 · utility
14Cited by
6References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 2, 2016 |
| Grant date | Aug 20, 2019 |
| Priority date | — |
| Expiry date | Dec 2, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14151
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to variant AAV capsid polypeptides, wherein the variant AAV capsid polypeptides exhibit increased transduction and/or tropism in human muscle tissue or cells as compared non-variant parent capsid polypeptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.