Magnetic bead aggregation assay system
US10386364B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 9, 2012 |
| Grant date | Aug 20, 2019 |
| Priority date | — |
| Expiry date | Sep 11, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2446/84
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
There is provided a method of aggregating a plurality of beads in a magnetic bead aggregation assay for subsequent analysis comprising: —providing magnetic beads comprising a capture probe for binding with said target analyte; —reacting the magnetic beads with the sample including a target analyte in a reaction chamber aggregating the magnetic beads in the presence of a magnetic field with the target analyte to allow formation of magnetic bead aggregates having physical properties detectable to enable characterization of the aggregates on an aggregate by aggregate basis using a detector to measure the physical properties of the aggregates. Further provided are a method and system for detecting analytes in a sample by characterizing the magnetic bead aggregates on an aggregate by aggregate basis by measuring physical properties of the aggregates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.