High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US10391072B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Mar 15, 2017 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | May 16, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Granules of racemic sodium ibuprofen dihydrate formed from components specified herein have very desirable properties and can be effectively used in conventional rotary press tableting equipment without operational difficulties often en-countered in actual practice. Their preparation by a wet granulation process, the wet granule compositions, formulations adapted for preparation of solid dosage forms utilizing a rotary press, solid dosage forms, and methods of preparing solid dosage forms in a rotary press are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.