Use of nanodiamonds for generating free radicals for therapeutic purposes under radiation
US10391172B2 · kind B2 · utility
2Cited by
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20Claims
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Assignee
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Key dates
| Filing date | Jul 12, 2013 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | Jul 12, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2982
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of nanodiamonds as drugs generating free radicals, in particular for treating tumors. The invention is based on generating free radicals on the surface of the nanodiamonds when they are exposed to radiation, for example ionizing radiation. In order to increase the effectiveness of the nanodiamonds, the nanodiamonds can be complexed with a radiosensitizing agent, such as a chemical molecule or an interfering RNA targeting a repairing gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.