Etomidate derivative and intermediate, preparation method and use thereof
US10392352B2 · kind B2 · utility
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19Claims
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Assignee
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Key dates
| Filing date | Oct 10, 2016 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | Oct 10, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P23/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses an etomidate derivative of Formula 1, or a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, a pharmaceutical composition and a kit comprising the same, as well as intermediates and methods for preparing the same, and use thereof. The etomidate derivative of the present invention not only has good anesthetic activity, rapid onset, and short duration of action, but also shows little inhibition to the secretion of corticosteroids in animals, and therefore has both favorable anesthetic effect and safety profiles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.