Oxazole derivatives that inhibit Syk
US10392373B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Sep 16, 2016 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | Sep 16, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is concerned with substituted oxazole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, autoimmune, allergic, hematological, inflammatory and degenerative disorders. In particular, the compounds of the invention are Syk inhibitors. The invention also relates to a process for manufacturing the compounds of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.