Patent · US Active

Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide and recovery of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide by electrochemical methods

US10392384B2 · kind B2 · utility

2Cited by

0References

8Claims

0Family size

Assignee

Bayer Pharma Aktiengesellschaft · DE

Inventors

Johannes Platzek · Berlin, DE
Kathrin Gottfried · Wuppertal, DE
Jens Assmann · Haan, DE
Giulio Lolli · Neunburg vorm Wald, DE

Key dates

Filing date	Aug 18, 2016
Grant date	Aug 27, 2019
Priority date	—
Expiry date	Aug 18, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC25B15/08
WIPO fieldSurface technology, coating
WIPO sectorChemistry

Abstract

The present invention relates to a novel process for preparing (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide of the formula (I) and recovering (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide of the formula (I) proceeding from (4R)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide of the formula ent-(I)

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.