Method for decreasing depression-like behavior with connective tissue growth factor (CTGF) inhibitor
US10392435B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Dec 6, 2017 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | Dec 6, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/304
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The methods of the present invention are useful for determining whether an individual has or is at risk of developing an affective disorder by detecting the expression level of connective tissue growth factor (CTGF) in a biological sample. The methods of the present invention are also useful for identifying compounds that modulate (e.g., decrease) the expression level or activity of CTGF. The present invention further provides therapeutic methods that target CTGF for the treatment of an affective disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.