Bispecific antibodies
US10392438B2 · kind B2 · utility
6Cited by
3References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 13, 2015 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | May 13, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to engineered heteromultimeric proteins, and more specifically, to methods for producing and purifying heterodimeric proteins, such as bispecific antibodies and. Methods for producing and purifying such engineered heterodimeric proteins and their use in diagnostics and therapeutics are also provided. The present invention also relates to a humanized antibody that specifically binds human TrkB and methods for producing and using the antibody to, inter alia, treat a hearing loss disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.