Human-derived anti-dipeptide repeats (DPRs) antibody
US10392447B2 · kind B2 · utility
1Cited by
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120Claims
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Key dates
| Filing date | Sep 30, 2015 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | Sep 30, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2814
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are novel human-derived dipeptide repeat (DPR) specific antibodies as well as synthetic variants and biotechnological derivatives thereof, preferably capable of binding C9ORF72 DPRs, as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for DPRs and DPR proteins such C9ORF72 DPRs are also disclosed. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.