Nucleic acid detection plate and detection system combined with piezoelectric sensing and loop-mediated isothermal amplification
US10392591B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 2, 2015 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | Jan 3, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2291/0427
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A nucleic acid detection plate comprises a piezoelectric sensor and at least a pipe flowing through the surface of the piezoelectric sensor, two valves intervally installed on the pipe relative to the upstream end of the piezoelectric sensor, the nucleic acid to be detected is blocked in the pipe between the two valves for isothermal amplification; the nucleic acid detection system comprises the nucleic acid detection plate described above, a thermostat capable of accommodating the nucleic acid detection plate; and a signal processor capable of being date connected to the piezoelectric sensor. The inventive method simplifies device structure in through coordinated detection by combination of thermostatic amplification and piezoelectric sensing, and improves detection efficiency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.