Nanocomposite scaffold for the in vitro isolation of cells

US10392594B2 · kind B2 · utility

Assignee

• Rensselaer Polytechnic Institute · US

Inventors

• Ryan J. Gilbert · Troy, US
• Elizabeth Hager Cothren · Frederick, US
• Gregory Patrick Desmond · Marshfield, US
• Marc Andrew Burnette · Menifee, US
• Erica Victoria Hoey · Floral Park, US
• Stephanie Christine Krom · Troy, US
• Clarissa May Herman · Troy, US

Key dates

• Filing date: Sep 28, 2015
• Grant date: Aug 27, 2019
• Expiry date: Sep 28, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2531/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention is directed to devices, methods and kits for cell-specific sorting of cells from a mixed population, e.g., from a tumor sample. Aspects of the invention combine aligned, electrospun microfibers with drug- or protein-releasing nanospheres to isolate cancer cells from tumor biopsies.