Method of generating human pancreatic cells
US10392600B2 · kind B2 · utility
0Cited by
16References
1Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 15, 2016 |
| Grant date | Aug 27, 2019 |
| Priority date | — |
| Expiry date | Aug 15, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. In accordance with the present invention, a selectable marker gene has been recombinantly targeted to the brachyury locus to allow the isolation and characterization of cell populations that comprise brachyury positive mesendoderm and mesoderm cells. The cell populations of the invention are useful for generating cells for cell replacement therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.