Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof

US10398159B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Thomas Subkowski · Schriesheim, DE
• Claus Bollschweiler · Heidelberg, DE
• Jens Wittenberg · Schifferstadt, DE
• Wolfgang Siegel · Schifferstadt, DE
• Ralf Pelzer · Rastenberg, DE

Key dates

• Filing date: Jun 1, 2017
• Grant date: Sep 3, 2019
• Expiry date: Jun 13, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J11/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.