Patent · US Active

Preparation of and formulation comprising a MEK inhibitor

US10398683B2 · kind B2 · utility

1Cited by
7References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 14, 2017
Grant dateSep 3, 2019
Priority date
Expiry dateDec 14, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to processes for preparing 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethyoxy)-amide, processes for preparing crystallized 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethyoxy)-amide, and intermediates useful therefore. Also provided herein are pharmaceutical compositions comprising this crystallized compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.