Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions
US10398758B2 · kind B2 · utility
9Cited by
65References
32Claims
0Family size
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Key dates
| Filing date | May 27, 2015 |
| Grant date | Sep 3, 2019 |
| Priority date | — |
| Expiry date | May 27, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2400/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.