Methods and compositions for recombinant dengue viruses for vaccine and diagnostic development
US10398768B2 · kind B2 · utility
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3References
14Claims
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Key dates
| Filing date | Nov 2, 2015 |
| Grant date | Sep 3, 2019 |
| Priority date | — |
| Expiry date | Nov 2, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce an epitope that is recognized by an antibody from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.