Cultured cell leaflet material
US10405975B2 · kind B2 · utility
0Cited by
3References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 22, 2016 |
| Grant date | Sep 10, 2019 |
| Priority date | — |
| Expiry date | Sep 22, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2537/10
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A prosthetic heart valve provided herein can include a cultured cell tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member. The cultured cell tissue can be obtained by culturing fibroblast cells, smooth muscle cells, or a combination thereof to form a sheet of cultured cells and chemically cross-linking the fibroblast cells while under tension. In some cases, the cultured cell tissue can be radially tensioned. In some cases, the cultured cell tissue can be bi-axially tensioned.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.