Compounds targeting proteins, compositions, methods, and uses thereof
US10406165B2 · kind B2 · utility
2Cited by
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25Claims
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Assignee
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Key dates
| Filing date | Mar 9, 2018 |
| Grant date | Sep 10, 2019 |
| Priority date | — |
| Expiry date | Mar 9, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides modulators of protein function, to restore protein homeostasis, including GSPT1 activity. The invention provides methods of modulating protein-mediated diseases, such as GSPT1-mediated diseases, disorders, conditions, or responses. Compositions are also provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as GSPT1-mediated diseases, disorders, and conditions, including cancer and astrogliosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.