Therapeutic vitamin D conjugates

US10406202B2 · kind B2 · utility

Assignee

• Extend Biosciences, Inc. · US

Inventors

• Tarik Soliman · Chester Springs, US
• Laura M. Hales · Cambridge, US
• Daniel B. Hall · Easton, US
• Christopher So · Henderson, US
• Howard Sard · Arlington, US
• Vishnumurthy Hegde · Chelmsford, US

Key dates

• Filing date: Jul 12, 2018
• Grant date: Sep 10, 2019
• Expiry date: Jul 12, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/60
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides non-hormonal vitamin D conjugated via the third carbon on the vitamin D backbone to parathyroid hormone (PTH) proteins that result in increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms.