Patent · US Active

Cell-penetrating bacterial E3-ubiqitin-ligases for use in immunotherapy

US10406215B2 · kind B2 · utility

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13Claims

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Assignee

WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER · DE

Inventors

Marie-Luise Lubos · Munster, DE
Alexander Schmidt · Havixbeck, DE
Christian Rueter · Munster, DE

Key dates

Filing date	Sep 22, 2014
Grant date	Sep 10, 2019
Priority date	—
Expiry date	Sep 22, 2034

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella and variants, fragments and immunomodulatory domains thereof, for use in immunotherapy. The present invention further relates to cell-penetrating effector proteins of type III secretion system (T3SS)-containing bacteria of the genus Salmonella or Shigella and variants, fragments and immunomodulatory domains thereof, for delivering cargo molecules into eukaryotic cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.