Patent · US Active

AAV vectors with expanded packaging capacity

US10406244B2 · kind B2 · utility

14Cited by
6References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 1, 2016
Grant dateSep 10, 2019
Priority date—
Expiry dateMay 11, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2750/14143
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to AAV vectors encoding variant capsid polypeptides that are more cationic as compared to a non-variant parent capsid polypeptide and/or another variant capsid polypeptide, and wherein the vector comprising the variant capsid polypeptide is capable of comprising a longer nucleic acid insert as compared to a vector encoding a non-variant parent capsid polypeptide and/or another variant capsid polypeptide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.