Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication

US10407410B2 · kind B2 · utility

Assignee

• ViiV Healthcare UK (No.5) Limited · GB

Inventors

• John F. Kadow · Wallingford, US
• B. Narasimhulu Naidu · Durham, US
• Manoj Patel · Berlin, US
• Michael A. Walker · Durham, US
• Tao Wang · Farmington, US
• Zhiwei Yin · Glastonbury, US
• Zhongxing Zhang · Wallingford, US
• Zhizhen Barbara Zheng · Cheshire, US

Key dates

• Filing date: May 9, 2017
• Grant date: Sep 10, 2019
• Expiry date: May 9, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.