Patent · US Active

Method for producing alpha-form crystal of reduced glutathione, and method for storing said crystal

US10407463B2 · kind B2 · utility

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1References
17Claims
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Assignee

Inventors

Key dates

Filing dateJun 3, 2016
Grant dateSep 10, 2019
Priority date
Expiry dateJun 4, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K5/08
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The invention provides a method of efficiently and stably producing α-form crystal of reduced glutathione, and a preservation method thereof. According to the invention, development of β-form crystal and/or transition to β-form crystal of reduced glutathione are suppressed by the coexistence of at least one kind of compound selected from the group of aliphatic amino acid, sulfur-containing amino acid, aromatic amino acid, an analogous compound and dipeptide, as a habit modifier, during production and preservation of an aqueous solution or α-form crystal of reduced glutathione.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.