Patent · US Active

Method for preparing AMG 416

US10407464B2 · kind B2 · utility

2Cited by

2References

14Claims

0Family size

Assignee

AMGEN INC. · US

Inventors

Jeroen BEZEMER · Thousand Oaks, US
Ying Chen · Newbury Park, US
Richard Crockett · Thousand Oaks, US
Kevin Crossley · Thousand Oaks, US
Sheng Cui · Lexington, US
Liang-Kun Huang
Sian JONES · Newbury Park, US
Asher LOWER · Moorpark, US
Krishnakumar Ranganathan · Oak Park, US

Key dates

Filing date	Apr 3, 2015
Grant date	Sep 10, 2019
Priority date	—
Expiry date	Aug 9, 2035

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P5/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method for preparing AMG 416, or a pharmaceutically acceptable salt thereof, is provided. AMG 416 is a synthetic, eight amino-acid selective peptide agonist of the calcium sensing receptor. It is being developed as an intravenous treatment of secondary hyperparathyroidism (SHPT) in hemodialysis patients with chronic kidney disease-mineral and bone disorder (CKD-MBD).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.